References
RESEARCH ROUNDUP
Abstract
In this regular feature, aesthetic nurse Claudia McGloin presents a brief synopsis of a range of recently published articles on medical aesthetics. Research roundup aims to provide an overview, rather than a detailed summary and critique, of the papers selected. Should you wish to look at any of the papers in more detail, a full reference is provided at the end of each study summary
One study explored the link between social media and dermatologist selection
An important protein for skin barrier structure and function is filaggrin. It is thought that mutations in the filaggrin gene FLG and loss of function may increase the dermal absorption of chemicals.
The main objective of this study was to confirm if dermal absorption of chemicals differs depending on FLG genotype. To conduct the study, the authors enlisted the help of 432 Swedish volunteers. The authors then carried out a quantitative polymerase chain reaction-based genetic screening for loss-of-function mutations and discovered 28 FLG null carriers.
Within this dermal exposure experiment, the authors exposed 23 FLG null and 31 wild-type carriers to three organic compounds common in the environment: the polycyclic aromatic hydrocarbon pyrene, the pesticide pyrimethanil and the ultraviolet-light absorber oxybenzone. To measure the concentrations of these chemicals in the volunteers' urine, the authors used liquid chromatography mass spectrometry over a 48-hour period after exposure.
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